| 008 |
|
200521n^^^^^^^^xx^a^^^^o^^^^^|||^u^eng^d |
| 024 |
7 |
|a TP155.2.E48 2013_ShyHannah |2 BU-Local |
| 245 |
10 |
|a Greener oxidation and purification methods for mechanochemical porphyrin synthesis |h [electronic resource]. |
| 260 |
|
|a Miami, Fla. : |b Barry University, |c 2013. |
| 300 |
|
|a viii, 39 leaves : |b ill. ; |c 28 cm |
| 490 |
|
|a Barry University Theses -- Honors Program. |
| 502 |
|
|a Thesis (Honors)--Barry University, 2013. |
| 504 |
|
|a Includes bibliographical references (leaves 37-39). |
| 506 |
|
|a Copyright Hannah Shy. Permission granted to Barry University to digitize, archive and distribute this item for non-profit research and educational purposes. Any reuse of this item in excess of fair use or other copyright exemptions requires permission of the copyright holder. |
| 520 |
3 |
|a Solvent- free chemistry has become popular because of the increased emphasis on waste reduction and lessening cost. Porphyrins are cyclic, organic compounds that have become important in the construction of larger, self-assembled systems. The traditional synthesis of porphyrins consists of an acid-catalyzed condensation of pyrrole and aldehyde to produce a precursor: porphyrinogen, which is then oxidized to become porphyrin. The traditional process is inefficient with yields lower than 30% and requires high-dilution solvent conditions to ensure the proper reaction takes place. We have been successful in developing a solvent-free approach using either a mortar and pestle or a ball mill. Grinding produces the cyclized product, porphyrinogen, which needs to be oxidized. We currently use the traditional method for this step and have focused on developing a green method. Here we present the results of our studies to develop a 100% green methodology for synthesis of these important organic molecules. |
| 533 |
|
|a Electronic reproduction. |c Barry University, |d 2020. |f (Barry University Digital Collections) |n Mode of access: World Wide Web. |n System requirements: Internet connectivity; Web browser software. |
| 535 |
1 |
|a Barry University Archives and Special Collections. |
| 830 |
0 |
|a Barry University Digital Collections. |
| 830 |
0 |
|a Theses and Dissertations. |
| 852 |
|
|a BUDC |c Theses and Dissertations |
| 856 |
40 |
|u http://sobekcmsrv.barrynet.barry.edu/AA00001951/00001 |y Click here for full text |
| 992 |
04 |
|a https:/budc.barry.edu/content/AA/00/00/19/51/00001/TP155_2_E48 2013_ShyHannahthm.jpg |
| 997 |
|
|a Theses and Dissertations |
